SEPARASE LOSS OF FUNCTION COOPERATES WITH THE LOSS OF P53 IN THE INITIATION AND PROGRESSION OF T- AND B-CELL LYMPHOMA, LEUKEMIA AND ANEUPLOIDY IN MICE.

Separase loss of function cooperates with the loss of p53 in the initiation and progression of T- and B-cell lymphoma, leukemia and aneuploidy in mice.

butter silk sarees pothys Cohesin protease Separase plays a key role in faithful segregation of sister chromatids by cleaving the cohesin complex at the metaphase to anaphase transition.Homozygous deletion of ESPL1 gene that encodes Separase protein results in embryonic lethality in mice and Separase overexpression lead to aneuploidy and tumorigene

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Genetic mapping of escalated aggression in wild-derived mouse strain MSM/Ms: association with serotonin-related genes

The Japanese wild-derived mouse strain MSM/Ms (MSM) retains a wide range of traits related to behavioral wildness, including high levels of emotionality and avoidance of humans.In this the gel bottle baby study, we observed that MSM showed a markedly higher level of aggression than the standard laboratory strain C57BL/6J.Whereas almost all MSM male

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